Page 211 - PRECONGRESS COURSE 06

With or without rec-hLH
Results from the ESPART trial: RCT investigating rLH supplementation for COS in poor reponders aligned with the Bologna
Outcome
r-hFSH + r-hLH (n=462)
r-hFSH (n=477)
P-value
Biochemical pregnancy, n (%)
80 (17.3)
114 (23.9)
0.020
Clinical pregnancy, n (%)
65 (14.1)
80 (16.8
0.323
Ongoing pregnancy, n (%)
51 (11.0)
59 (12.4)
0.599
Live birth, n (%)
49 (10.6)
56 (11.7)
0.663
15
30-5-2017
Humaidan et al., Hum Reprod, 2017
Individualised dosing regime and ovarian response according to AMH
60
40
20
Individualised dosing of follitropin delta resulted in more women with target ovarian response (8–14 oocytes)
Follitropin delta Follitropin alfa
0
0 10 20 30 40 50
AMH (pmol/L)
Nyboe Andersen AN, et al. Fertil Steril 2016
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Women with 8–14 oocytes retrieved (%)