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PSC-derived (male) gametes: how far are we in vitro?
?
functional gametes!
Zhou et al., Cell Stem Cell 2016
functional gametes!
?
functional
no
gametes!
Hibake et al., Nature 2016
Chuva de Sousa Lopes 7
PSC-derived (male) gametes: how far are we?
Can human PSCs can form FUNCTIONAL gametes?
-We don’t know
-Unethical test germline transmission in chimeric animals
stem cells <> (4N) embryo
Papa!
Chuva de Sousa Lopes 8
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PRECONGRESS COURSE 01 I BARCELONA, SPAIN – 1 JULY 2018 39
