Page 50 - Eshre 2018
P. 50
Precursor classification: acceptance WHO 2016.
PRECURSOR TERMINOLOGY
CIS - (TIN) - IGCNU
Overview pathology GCNIS related TGCT.
PRE-INVASIVE:
Early gonadal development
seminoma embr. carc.
COMMON PRECURSOR
Blocked PGC/gonocyte (EMBRYONIC GERM CELL)
GCNIS (GB-DSD)
INTRATUBULAR:
70%
~ 7 years
INVASIVE:
PURE or MIXED
seminoma
embr.carc.
teratoma
germ cells
hCG
choriocarc.
PLURIPOTENT (TOTI-/OMNI-)
AFP
yolk sac tum.
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