Page 65 - Eshre 2018
P. 65

 Learning objectives
To learn:
-the state of the art in the field of in vitro male germ cell differentiation
-the present murine and human experimental models recapitulating, in full or in part, the process of spermatogenesis in vitro
-the advantages and limitations of each system
-the direct derivation of haploid male germ cells from ESCs/iPSCs
-the testicular endocrine function in vitro
   PRIMORDIAL GERM CELLS (PGC)
GONOCYTES
PRE-SPERMATOGONIA
  birth
Differentiation Self-renewal
SPERM SPERMATOGONIAL STEM CELLS (SSC)
      SPERMATOGONIAL STEM CELLS (SSC)
    Page 59 of 130
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