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PCOS endometrium in ovulatory cycles
Suspect
• Altered glucose tolerance
• High insulin
• Severe hyperandrogenism
• High inflammatory status (fat) • Amenorrhea
• No P4 treatments
• No Metformin
• Abnormal bleeding pattern
PCOS endometrium in ovulatory cycles
• Keep low threshold for assessing further
• Endometrium does not
have to be hyperplastic to have cancer
• Progestins
• Other treatments if
cancer
• Treatments and prevention
• How often should progestins be used?
• Any preferences?
• LNG IUS vs p.o.
progestins
• Metformin?
• Weight reduction/BS
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