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Rationale for Aromatase Inhibitors in Ovulation Induction
 Interferes with inappropriate estrogen feedback at the hypothalamus
Corresponding rise in FSH secretion from the pituitary gland
 Shorter half life than clomiphene
Less early pregnancy exposure and cumulative effects
 Favovable Reproductive Effects (No ER Antagonism) vs. Clomiphene
More monofollicular ovulation More favorable endometrial effects
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