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EXTRAORDINARY GENETIC DIVERSITY IN HUMAN EMBRYOS AT IMPLANTATION
Vanneste E et al.; David H Ledbetter Nature Medicine 15, 490 - 491 (2009)
Elpida Fragouli et al. (2013)
mCGH on cleavage stage human embryos
754 embryos from 113 couples
2,468 distinct chromosome imbalances 49% trisomies and 51 monosomies 130 out of 754 (17%) were ‘euploid’
mCGH on human blastocysts
1,046 blastocysts from 188 couples 1,113 distinct aneuploidies
53 % trisomies and 47% monosomies 42% of embryos were ‘euploid’
Human Genetics 132:1001-1013
EXTRAORDINARY GENETIC DIVERSITY IN HUMAN EMBRYOS AT IMPLANTATION
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