Page 27 - PCC11

Learning objectives
• DNA fragmentation: what it is all about?
• how to test DNA fragmentation?
• should I bother about DNA fragmentation?
• a test result: what now?
• take home messages
Take home messages
• DNAfragmentation:
happens during normal spermatogenesis
• reproductive consequences:
only associations not always well-evidenced
• target group for testing in a clinical setting remains unclear: repeated ART failure? repeated miscarriage?
• poorly-standardized proxy tests (testing renders sperm unsuitable for further clinical use)
• at present no well-proven (and studied) therapies to remedy subfertitity in association with high DF
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PRECONGRESS COURSE 11 I BARCELONA, SPAIN – 1 JULY 2018 27
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