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(Shirasawa and Terada, Reprod Med Biol. 2017)
IN VIVO VERSUS EX VIVO IVM
IN VIVO IVM
EX VIVO IVM
Need surplus intervention
No need of surplus intervention
Need physicians and lab experience for a good oocyte recovery rate
Only lab experience needed
Both ovaries are aspirated, can provide good recovery rate
Usually one ovary, comparative studies needed
Risk of cancer cell spillage (ovarian cancer)
Safe
Good conditions for oocyte developmental capacity:
▪ oocytes kept at 37°C
▪ oocytes derived from selected antral follicles (6-12 mm)
Conditions less optimal for oocyte
developmental capacity:
▪ temporary exposure of oocytes at 4°C
▪ unselected follicle sizes including very small follicles (< 6mm)
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PRECONGRESS COURSE 11 I BARCELONA, SPAIN – 1 JULY 2018 85