Page 42 - PCC13
P. 42
Quality of included studies
RCT
RoB‐2
https://sites.google.com/site/riskofbiastool/
Non‐randomised studies
Robins‐1 tool
https://sites.google.com/site/riskofbiastool/
Case‐control studies
Newcastle Ottawa Scale
http://www.ohri.ca/programs/clinical_epide miology/nosgen.pdf
Prognostic studies
Quips
http://www.biomedcentral.com/content/sup plementary/1546‐0096‐12‐19‐S1.pdf
Diagnostic studies
Quadas 2
http://www.bristol.ac.uk/social‐community‐ medicine/projects/quadas/quadas‐2/
Systematic review
AMSTAR
http://amstar.ca/Amstar_Checklist.php
Meta‐analysis
Optional part of systematic review Same patients, same treatment
Unit of analysis = unit of randomisation uses forest plot to summarize studies clearer picture
precision of treatment effect
Systematic reviews
Meta-analyses
42
Page 36 of 84
