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Review of Mitochondrial Replacement Technology with reference list:
Assisted reproductive technologies to prevent human mitochondrial disease transmission. Greenfield, Braude, Flinter, Lovell‐Badge, Ogilvie, Perry. Nature Biotechnology 35, 1059‐1068 (2017)
Mitochondrial diseases
Mitochondrial diseases. Gorman, Chinnery, DiMauro, Hirano, Koga, McFarland, Suomalaine, Thorburn Zeviani and Turnbull. Nature Reviews Primers. 2, 16080 (2016)
Holt IJ, Harding AE, Morgan‐Hughes JA. Deletions of muscle mitochondrial DNA in patients with mitochondrial myopathies. Nature 331:717–19. (1988).
Turnbull & Taylor. Mitochondrial DNA mutations in human disease. Nature Reviews Genetics, 6, 389‐401, (2005)
Tuppen HA, Blakely EL, Turnbull DM, Taylor RW. Mitochondrial DNA mutations and human disease. Biochim. Biophys. Acta 1797:113–28. (2009)
Stewart JB, Larsson N‐G Keeping mtDNA in Shape between Generations. PLoS Genet 10(10): e1004670 (2014)
Smeets, H. J., Sallevelt, S. C., Dreesen, J. C., de Die‐Smulders, C. E. & de Coo, I. F. Preventing the transmission of mitochondrial DNA disorders using prenatal or preimplantation genetic diagnosis. Ann. NY Acad. Sci . 1350, 29–36 (2015)
Cytoplasmic transfer:
Goddard & Pratt. Control of events during early cleavage of the mouse embryo: an analysis of the ‘2‐cell block’. Development 111‐133 (1983)
Pratt & Muggleton‐Harris. Cycling cytoplasmic factors that promote mitosis in the cultures 2‐cell mouse embryo. Development, 104,115‐120 (1988)
Barritt, J.A., Willadsen, S., Brenner, C., and Cohen, J. Cytoplasmic transfer in assisted reproduction. Hum. Reprod. Update. ; 7: 428–435 (2001)
Chen, S.H., Pascale, C., Jackson, M., Szvetecz, M.A., and Cohen, J. A limited survey‐based uncontrolled follow‐up study of children born after ooplasmic transplantation in a single centre. Reprod. Biomed. Online. 33: 737–744 (2016)
Mitochondrial donation science:
Craven, L. et al. Pronuclear transfer in human embryos to prevent transmission of mitochondrial DNA disease. Nature 465, 82–85 (2010)
Tachibana, M. et al. Mitochondrial gene replacement in primate offspring and embryonic stem cells. Nature 461, 367–372 (2009)
Hyslop, L.A. et al. Towards clinical application of pronuclear transfer to prevent mitochondrial DNA disease. Nature 534, 383–386 (2016).
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