Page 127 - PCC15

Following hCG/EGF treatment, in Excess androgen induced abnormalities in the morphology and
10-5 M androstenedione-treated function of developing oocytes, which impairs oocyte meiotic
follicles, competence.
 Oocyte meiotic maturation
July 2018 ESHRE 2018
lower
 Failure of spindle assembly
higher
 Misaligned chromosomes more
frequent
Does clinical research follow principles of ovarian physiology
July 2018 ESHRE 2018
The transition from preantral to antral follicular stage ≈ 70 days
Testosterone in excess to 5.5 mg/d may be detrimental to follicle develo
pment
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PRECONGRESS COURSE 15 I BARCELONA, SPAIN – 1 JULY 2018 127