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IVF with a single blastocyst versus single cleavage stage: a randomized study
• 351 infertile women (below 36 years) were randomized to ET of a single cleaved embryo or a single blastocyst.
• There was significantly higher pregnancy and delivery rate in the blastocyst stage group.
(Papanikolaou 2006)
Cumulative live birth rates were similar
after day 3 and 5 after cryo‐embryos
• However,thecumulativelivebirthrateswere 52.6% for cleavage‐stage and 52.5% for blastocyst‐stage transfers (P=0.989).
transfer (De vos et al., 2016)
• Livebirthratesperstartedcyclewere significantly lower after transferring the fresh single cleavage‐stage embryo, compared to a blastocyst (31.3% and 37.8%, respectively, P=0.041).
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PRECONGRESS COURSE 15 I BARCELONA, SPAIN – 1 JULY 2018 15