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Pre‐term delivery
• Two separate meta‐analysis of observational studies have confirmed that IVF pregnancies from blastocyst stansfer were associated with a higher risk of premature labor. 95% CI less than 37 weeks 1.27 (1.22‐ 1.31) and very preterm labor less than 32 weeks 1.22 (1.10‐1.35). (Maheshwari et al. 2013, Dar et al 2014)
• These findings were not confirmed in one Australian study. (Chambers et al., 2015)
Increased perinatal mortality
• Several studies reported significantly
higher perinatal mortality after blastocyst
transfer (Dar et al., 2014; Ginström Ernstad et al., 2016; Martins et al., 2016)
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