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Why do we still continue extended culture?
• Most clinicians ignore:
– the percentage of patients who do not have transfer as no embryos reached blastocyst stage.
– Complications associated with blastocyst transfer
– No higher cumulative pregnancy rate after blastocyst ET per started cycle.
Conclusion
• There is small (low quality) evidence of improved pregnancy rate per cycle after day 5 transfer. However, there is an extensive literature which shows no difference in pregnancy rate between day 3 and day 5.
• There is no significant difference in the cumulative pregnancy rate between Day 3 and Day 5 embryo transfer.
• There are certain risk of blastocyst transfer.
• The WHO idea of extended culture is to transfer one blastocyst.
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PRECONGRESS COURSE 15 I BARCELONA, SPAIN – 1 JULY 2018 23