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STAR
• Randomization PGS vs no-PGS 1:1
• 588 eligible woman with a transfer
– 274 with PGS / 314 without PGS
– Thus more no transfers with PGS
• Ongoing pregnancies
– 136 with PGS / 144 without PGS
– Per ET 49.6% (136/274) vs 45.9% (144/314)
– Per OPU 39.0% (136/349) vs 41.3% (144/349)
• FRET cycles not even included..... Munné, et al (ASRM 2017, O-43)
WARNING! ESTIMATES! (10% no ET in control)
How should we inform patients?
• Chances of having a baby per woman
What are our
Should we go chances of
for PGS? having a baby?
– PGS 1.0
– PGS 2.0
will decrease LBR per started cycle almost no data, no increase in LBR perhaps fewer miscarriages
• Secondary outcomes?
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