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Mitochondrial donation: Ethical questions
• What is safe enough?
• Does it matter if there is a mismatch between mitochondrial haplotype origin and that of the donor?
• Who is taking the risk?
• Does it matter that when we use PBT, we are using ‘egg offalʼ to create the new person, and that is a person who would never have existed in nature?
• Should the technology be restricted to replacing males only – no intergenerational effects?
Clinical correlates:
Or how do we use this information critically
1. Understanding and avoiding mitochondrial genetic disease
2. Understanding and improving fertility and IVF
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PRECONGRESS COURSE 15 I BARCELONA, SPAIN – 1 JULY 2018 93
