Main programme

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Tuesday 03 July 2018

08:30 - 09:30
Session 26: The ageing man
Chairmen
Jackson Kirkman-Brown, United Kingdom
Francesca Vidal, Spain
08:30 - 09:00
Mechanistic basis of ageing effects
John Aitken, Australia
09:00 - 09:30
The ageing male germ cell
Jörg Gromoll, Germany

08:30 - 09:30
Session 27: In vitro post-implantation models
Chairmen
Bjorn Heindryckx, Belgium
Cristina Eguizabal, Spain
08:30 - 09:00
The use of novel imaging to decipher lineage segregation in the early embryo
Nicolas Plachta, Singapore Rep. of
09:00 - 09:30
Self-organization of the human embryo in the absence of maternal tissues
Magdalena Zernicka-Goetz, United Kingdom

08:30 - 09:30
Session 28: Big data in endometriosis – hope or hype?
Chairmen
Pedro Barri, Spain
Krina Zondervan, United Kingdom
08:30 - 09:00
Big data in understanding disease
David Hunter, United Kingdom
09:00 - 09:30
Big data in endometriosis
Stacey Missmer, U.S.A.

08:30 - 09:30
Session 29: ASRM exchange session: Maximizing the chance of pregnancy for every patient: An intention-to-treat analysis
Chairmen
Christos Coutifaris, U.S.A.
Ramon Aurell Ballesteros, Spain
08:30 - 09:00
A rational approach to the management of the older and low response patient undergoing ART
Owen Davis, U.S.A.
09:00 - 09:30
Every last baby out of every last egg: Does PGS really improve the chance of pregnancy for every patient?
Richard J. Paulson, U.S.A.

08:30 - 09:30
Session 30: WHO session: WHO and fertility care: Time to engage?
Chairmen
Roy G Farquharson, United Kingdom
Thabo Matsaseng, Switzerland
08:30 - 08:35
Introduction: HRP vision and goals regarding infertility
James Kiarie, Switzerland
08:35 - 08:45
WHO priorities in infertility and fertility care
Thabo Matsaseng, Switzerland
08:45 - 08:55
Estimation of prevalence of infertility from cross-section surveys (DHS) using time-to-pregnancy approach: preliminary results of a pilot study
Thabo Matsaseng, Switzerland
08:55 - 09:05
The landscape of IVF in lower and middle income countries
Tendai Chiware, U.S.A.
09:05 - 09:15
Developing ART practice in low and middle income countries
Willem Ombelet, Belgium
09:15 - 09:25
Discussion
09:25 - 09:30
Closing remarks
James Kiarie, Switzerland

08:30 - 09:30
Session 31: Nurses/Midwives invited session
Chairmen
Valerie Blanchet De Mouzon, France
Chairman to be announced
08:30 - 09:00
Use of ultrasound at embryo transfer - is it necessary?
Alison McTavish, United Kingdom
09:00 - 09:30
Family planning, knowledge about fertility and lifestyle prior to conception; nurses and midwives as key persons in preconception care
Tanja Tyden, Sweden

08:30 - 09:30
Product theatre

09:30 - 10:00
Coffee break

09:45 - 10:45
Product theatre

10:00 - 11:30
Session 32: Updates in embryo morphokinetics
Chairmen
Ioannis Sfontouris, Greece
Marcos Meseguer Escriva, Spain
10:00 - 10:15
The effect of oocyte vitrification on subsequent embryo developmental morphokinetics and blastocyst formation: a prospective time-lapse sibling oocyte study
Stefanie De Gheselle, Belgium
10:15 - 10:30
Duration of blastomere movement post first cytokinesis is an effective predictor for the clinical pregnancy after fresh cleaved embryo transfer: in a minimal stimulation program.
Kazuki Ohata, Japan
10:30 - 10:45
Time Lapse assessment of the occurrence and clinical outcome of direct cleavage in a population of 10,529 embryos cultured to the blastocyst stage
Susan Montgomery, United Kingdom
10:45 - 11:00
Is there a relation between embryo early cleavage abnormalities and blastulation or implantation rates? A retrospective time-lapse imaging study
Roussila Naam Ouarezki, France
11:00 - 11:15
Partial embryo compaction: what’s behind? Morphokinetic origins and chromosomal status
Cristina Lagalla, Italy
11:15 - 11:30
Time-lapse and NGS evaluation of human embryos cultured in single medium versus sequential media: a prospective randomized pilot study
Zhihong Yang, U.S.A.

10:00 - 11:30
Session 33: Intrauterine insemination and flushing
Chairmen
Janneke den Hartog, The Netherlands
Roberto Matorras, Spain
10:00 - 10:15
The effect of intra-uterine slow-release insemination (SRI) on the pregnancy rate in women designated for standard intra-uterine insemination (IUI) – A multicentre randomized, controlled trial
Julian Marschalek, Austria
10:15 - 10:30
What is in unexplained subfertility the impact of gonadotropins or clomiphene citrate on endometrial thickness: a secondary analysis of a trial on intrauterine insemination
Noor Danhof, The Netherlands
10:30 - 10:45
A cost-effectiveness analysis of ovarian stimulation with follicle stimulating hormone (FSH) compared with clomiphene citrate (CC) in intra uterine insemination (IUI)
Noor Danhof, The Netherlands
10:45 - 11:00
Is intrauterine insemination with ovarian stimulation effective in couples with unexplained subfertility?
Rik van Eekelen, The Netherlands
11:00 - 11:15
Tubal flushing with oil- or water-based contrast medium at hysterosalpingography for infertility: 3-year outcome of a randomized clinical trial
Joukje van Rijswijk, The Netherlands
11:15 - 11:30
Does tubal flushing with oil- versus water-based contrast at hysterosalpingography increase the chance of a second child; long term follow-up of the H2Oil RCT.
Nienke van Welie, The Netherlands

10:00 - 11:30
Session 34: Launch of the international evidence-based guideline for the assessment and management of polycystic ovary syndrome (PCOS)
Chairmen
Basil C. Tarlatzis, Greece
Antonio Pellicer, Spain
10:00 - 10:20
Building an international PCOS guideline: Initiative, process and translation
Helena Teede, Australia
10:20 - 10:40
International guideline on PCOS: Diagnosis and treatment
Joop Laven, The Netherlands
10:40 - 11:00
Guideline recommendations: Treatment, emotional wellbeing and pregnancy
Terhi Piltonen, Finland
11:00 - 11:30
Panel discussion
Bart C.J.M. Fauser, The Netherlands
Angelica Lindén Hirschberg, Sweden
Joop Laven, The Netherlands
Robert John Norman, Australia
Terhi Piltonen, Finland
Daniela Romualdi, Italy
Juha S. Tapanainen, Finland
Helena Teede, Australia

10:00 - 11:30
Session 35: Genetic causes of male infertility
Chairmen
Christine Wyns, Belgium
Luis Bassas Arnau, Spain
10:00 - 10:15
Analysis of the chromosome territories dynamic in male germ cells and its association to male infertility
Mireia Solé, Spain
10:15 - 10:30
The altered testicular environment in patients with Klinefelter Syndrome
Dorien Van Saen, Belgium
10:30 - 10:45
A heterozygous DNAJB13 mutation induces multiple morphological and structural abnormalities to the sperm flagella (MMSAF) and may be a cause of idiopathic asthenozoospermia
Li Weina, China
10:45 - 11:00
Defective H3K9 demethylation of the male genome and abnormal first mitosis observed in mouse oocytes injected with human round spermatids
Yoshiteru Kai, Japan
11:00 - 11:15
SPANX A/D subfamily plays a key role in nuclear organisation, metabolism and flagellar-motility of human spermatozoa.
Nerea Subiran, Spain
11:15 - 11:30
Copr5is associated with Miwi and modulated the piRNA pathway, a possible mechanism involved in the human teratozoospermia sperm phenotype
Samir Hamamah, France

10:00 - 11:30
Session 36: IVF laboratory techniques and management
Chairmen
Cecilia Westin, Sweden
Lluc Coll, Spain
10:00 - 10:15
A two-step protocol for oocyte In Vitro Maturation in PCO/PCOS patients increases the yield and quality of usable embryos and results in ongoing pregnancies
Flor Ines Sanchez Ramos, Belgium
10:15 - 10:30
Assisted oocyte activation significantly increases fertilization and pregnancy rates resulting in healthy live births in patients with oocyte activation deficiencies
Davina Bonte, Belgium
10:30 - 10:45
Three babies born after pronuclear transplantation in young women with unexplained infertility and repeated implantation failure of euploid embryos
Pavlo Mazur, Ukraine
10:45 - 11:00
Blastocysts collapse as an embryo marker of low implantation potential a time-lapse study
Romualdo Sciorio, United Kingdom
11:00 - 11:15
The impact of dry incubation on osmolality of media in time-lapse culture dishes
Georgia Carpenter, New Zealand
11:15 - 11:30
Utility of the Vienna consensus on ART Laboratory Performance Indicators for managing multiple IVF laboratories performance
Geoffrey Howard Trew, United Kingdom

10:00 - 11:30
Session 37: Endometriosis and endometrium: clinical research
Chairmen
Petya Andreeva, Bulgaria
Nikolaos P. Polyzos, Spain
10:00 - 10:15
Endometrial scratching by pipelle biopsy in IVF (the PIP study): A pragmatic randomised controlled trial
Sarah Lensen, New Zealand
10:15 - 10:30
The impact of non-cavity distorting intramural fibroids on IVF outcomes: A systematic review and meta- analysis
Mukhri Hamdan, Malaysia
10:30 - 10:45
Supplementation in adolescent girls with endometriosis (SAGE): A double blind, randomized, placebo-controlled trial
James Nodler, U.S.A.
10:45 - 11:00
The Endometriosis Fertility Index (EFI) can be estimated accurately prior to surgical treatment of endometriosis
Carla Tomassetti, Belgium
11:00 - 11:15
The effect of different IVF protocols for women with endometriosis on their IVF outcomes: A Systematic review and Meta-Analysis
Khine Khine Lwin, Malaysia
11:15 - 11:30
Nationwide cohort study of the risk of major adverse cerebrovascular and cardiovascular events in the Asian women with endometriosis
Hsin-Ju Chiang, Taiwan R.O.C.

11:00 - 12:00
Product theatre

11:45 - 13:00
Industry sponsored symposium

11:45 - 12:45
Session 38: European and global ART monitoring
Chairmen
Carlos Calhaz-Jorge, Portugal
Fernando J. Prados-Mondéjar, Spain
11:45 - 12:15
European IVF-monitoring of ART and development of a strategy for vigilance
Christian De Geyter, Switzerland
12:15 - 12:30
ICMART World Report 2014
Geoffrey David Adamson, U.S.A.
12:30 - 12:45
Gender inequality and utilisation of assisted reproductive technology: an international analysis
Georgina Chambers, Australia

11:45 - 12:45
Session 39: New aspects in polycystic ovary syndrome
Chairmen
Daniela Romualdi, Italy
Rafael Bernabeu - Perez, Spain
11:45 - 12:15
First line treatment in PCOS: what to do?
Fulco Van der Veen, The Netherlands
12:15 - 12:45
Does race and ethnicity matter for metabolic risks in PCOS?
Robert John Norman, Australia

11:45 - 12:45
Session 40: Errors in IVF: Do they occur and how many?
Chairmen
Søren Ziebe, Denmark
Josep Santalo, Spain
11:45 - 12:15
To err is human: even in IVF
Dominique De Ziegler, France
12:15 - 12:45
This is how many errors occur in the IVF lab: a true analysis
Maria Jose De Los Santos, Spain

11:45 - 12:45
Session 41: Focus on blastocyst stage
Chairmen
Roger Sturmey, United Kingdom
Gustavo Tiscornia, Spain
11:45 - 12:00
Predicting blastocyst formation rate using a hierarchical and data mining-based statistical model
Jazmina Yao Serna, Japan
12:00 - 12:15
Blastocyst morphology grading: what is the most important predictor of live birth when accounting for endometrial receptivity? A multicentre analysis of 2477 single blastocyst transfers.
Ashleigh Storr, Australia
12:15 - 12:30
Predicting live birth by combining cleavage- and blastocyst-stage time-lapse variables using a hierarchical and a data mining-based statistical model
Satoshi Kawachiya, Japan
12:30 - 12:45
Day 5 versus Day 6 fresh and frozen blastocyst transfer cycle outcomes: a systematic review and meta-analysis
Astrid Finet, France

11:45 - 12:45
Session 42: Nursing and midwifery
Chairmen
Helen J. Kendrew, United Kingdom
Clara Pardos Torrents, Spain
11:45 - 12:00
Facilitators and barriers affecting help seeking of infertile women in the United States: A systematic review
Morine Cebert, U.S.A.
12:00 - 12:15
A feasibility and acceptability study of a novel self-help coping intervention for recurrent miscarriage
Sarah Bailey, United Kingdom
12:15 - 12:30
A retrospective observational study to compare the success rate of embryo transfer between Doctors and Nurse Practitioners in a nurse-led fertility centre.
Jane Mutch, United Kingdom
12:30 - 12:45
The importance of a genetic link between siblings after oocyte donation
Sara Somers, Belgium

13:00 - 14:00
SIG Reproductive Endocrinology members' meeting
SIG presentation
Daniela Romualdi, Italy

13:00 - 14:00
Lunch break

14:00 - 15:15
Industry sponsored symposium

14:00 - 15:00
Session 43: MHR symposium: First trimester biomarkers of impaired placentation
Chairmen
Chris Barratt, United Kingdom
Beatriz Alvaro Mercadal, Spain
14:00 - 14:30
Replication of Cytomegalovirus and Zika virus in first-trimester human placentas, mechanisms of viral pathogenesis and host cell defense
Lenore Pereira, U.S.A.
14:30 - 15:00
Cell-free fetal hemoglobin as a biomarker of impaired place
Stefan Hansson, Sweden

14:00 - 17:00
Session 44: Live surgery session
Chairmen
Michelle Nisolle, Belgium
Antoine Watrelot, France
Filipa Beja Osorio, Portugal
Antonio Setubal, Portugal
Attilio Di Spiezio Sardo, Italy

14:00 - 15:00
Session 45: Managing embryo stress in preimplantation development
Chairmen
Rita Vassena, Spain
Stéphane Viville, France
14:00 - 14:30
Nuclear reprogramming and chromatin functions in oocytes and preimplantation embryos
K.E. Latham, U.S.A.
14:30 - 15:00
Mitochondrial stress in preimplantation development and opportunities for treatment
Rebecca Robker, Australia

14:00 - 15:00
Session 46: Patient session: Surrogacy - the patients' perspective
Chairmen
Satu Rautakallio-Hokkanen, Finland
Klaudija Kordic, Croatia
Afroditi Alexopoulou, Greece
14:00 - 14:20
Surrogacy in Portugal - from struggle to accomplishment
Ana Galhardo, Portugal
14:20 - 14:40
Surrogacy and stratified kinship
Amrita Pande, South Africa
14:40 - 15:00
What is it like to be a wombless woman in the age of ART’s? Patients’ perspectives on gestational surrogacy in Finland
Kaisa Kivipuro, Finland

14:00 - 15:00
Session 47: How to increase people's fertility awareness?
Chairmen
Giuliana Baccino, Spain
Désirée Garcia Garcia, Spain
14:00 - 14:30
Development and impact of fertility campaigns
Lone Schmidt, Denmark
14:30 - 15:00
Preconceptional personalised mHealth lifestyle coaching: \rFirst results of a randomized controlled trial in couples undergoing IVF/ICSI treatment
Régine P.M. Steegers-Theunissen, The Netherlands

15:15 - 16:30
Session 48: Effects on testicular development and germ cell differentiation
Chairmen
Stefan Schlatt, Germany
Farners Amargant, Spain
15:15 - 15:30
Exposure to acetaminophen and ibuprofen affects fetal germ cell development in both sexes in rodent and human
Rod Mitchell, United Kingdom
15:30 - 15:45
Acute myeloid leukemia (AML) impaired mouse male fertility by affecting testicular growth factors, premiotic/miotic and posmiotic spermatogenic cell counts
Mahmoud Huleihel, Israel
15:45 - 16:00
CRISPR/cas9 mediated HSD17B3 gene mutation on mouse Leydig cells: Effectivity of CRISPR/cas9 on testosterone synthesis pathway
Nida Karahan, Turkey
16:00 - 16:15
Busulfan distinctly affected Sertoli cell activity in immature mice
Mahmoud Huleihel, Israel
16:15 - 16:30
The nuclear envelope: an unknown actor of human spermiogenesis
Catherine Metzler-Guillemain, France

15:15 - 16:30
Session 49: Premature Ovarian Insufficiency and poor ovarian response
Chairmen
Georgios Lainas, United Kingdom
Carlos Dosouto, Spain
15:15 - 15:30
High resolution array comparative genomic hybridization contribution to uncover genetic etiologies of idiopathic premature insufficiency: a cohort study
Asma Sassi, Belgium
15:30 - 15:45
ACTH-stimulation in women with low functional ovarian reserve (LFOR) confirms adrenal origin of hypo-androgenism
Vitaly Kushnir, U.S.A.
15:45 - 16:00
Are serum LH levels at the initiation of ovarian stimulation associated with oocyte retrieval yield after GnRH agonist triggering?
Biljana Popovic - Todorovic, Belgium
16:00 - 16:15
Luteal phase stimulation compared with conventional follicular phase stimulation in poor ovarian responders: Results of a randomized control trial
Joaquin Llacer, Spain
16:15 - 16:30
Double stimulation in a single menstrual cycle in patients with reduced ovarian reserve: hormonal characteristics, cumulus cell gene expression, embryological and clinical outcome
Bella Martazanova, Russia C.I.S.

15:15 - 16:30
Session 50: Genetic and epigenetic impact of assisted reproductive technologies
Chairmen
Antonio Capalbo, Italy
Nuno Costa-Borges, Spain
15:15 - 15:30
Increased heteroplasmic load of coding mitochondrial DNA variants in tissues from ART children
Filippo Zambelli, Spain
15:30 - 15:45
Hypomethylation of imprinted genes in term placenta samples conceived by IVF/ICSI is associated with concomitant changes in post-translational histones modifications
Cécile Choux, France
15:45 - 16:00
Ovarian stimulation for IVF and risk of primary breast cancer in BRCA1/2 mutation carriers
Ron Van Golde, The Netherlands
16:00 - 16:15
Higher gonadotropin dosage and longer ovarian hyperstimulation do not influence aneuploidy rates
Chelsea Canon, U.S.A.
16:15 - 16:30
Correlation between Embryo Ploidy Status and ovarian response after controlled ovarian Stimulation in ART cycles
Srividya Seshadri, United Kingdom

15:15 - 16:30
Session 51: Immunologic and other treatment options in RM/RIF
Chairmen
Bettina Toth, Austria
Montse Barragan, Spain
15:15 - 15:30
Effect of Administration of Intravenous intralipid on implantation rate in women with implantation failure after IVF/ICSI: A randomized controlled trial
Neeta Singh, India
15:30 - 15:45
Recombinant Human Granulocyte - Colony Stimulating Factor (rhG-CSF) in women with unexplained Recurrent Pregnancy Losses (RESPONSE Study): randomised, double-blind, multicentre, placebo controlled trial
Abey Eapen, U.S.A.
15:45 - 16:00
A reduction in uterine Natural Killer (uNK) cell density in response to luteal-phase endometrial scratch (ES) is associated with improved pregnancy outcome
Mariam Lokman, United Kingdom
16:00 - 16:15
Combinatorial use of Endometrial Receptivity Array (ERA) and PGT-A can improve the clinical outcome in cases with previous ART failures
Necati Findikli, Turkey
16:15 - 16:30
Immune therapies for women with history of unsuccessful implantation undergoing IVF/ICSI treatment - A Cochrane collaboration systematic review
Sonia Asif, United Kingdom

15:15 - 16:30
Session 52: Reproductive epidemiology, socio-cultural aspects and health economy
Chairmen
Virginie Rozée, France
Andrea Bernabeu, Spain
15:15 - 15:30
The DOD (Distance Oocytes Donation) strategy: A safe, efficient and “patient friendly” way to overcome lack of egg’s donors in different countries
Federica Moffa, Spain
15:30 - 15:45
You did not turn up… I did not realise I was invited…: Understanding male attitudes towards fertility awareness and poor engagement
Bola Grace, United Kingdom
15:45 - 16:00
Risk of prostate cancer in ICSI treated men
Yahia Al-Jebari, Sweden
16:00 - 16:15
The Canadian Assisted Reproductive Technologies Register (CARTR) Plus database: A validation study
Vanessa Bacal, Canada
16:15 - 16:30
Assisted reproductive technology (ART) treatment and risk of ovarian cancer
Anja Pinborg, Denmark

16:30 - 17:00
Coffee break

17:00 - 18:15
Industry sponsored symposium

17:00 - 18:00
Session 53: Machine learning and artificial intelligence
Chairmen
Nick Raine-Fenning, United Kingdom
Chairman to be announced
17:00 - 17:15
A pre-treatment counselling tool for predicting the cumulative probability of live birth
Neerujah Balachandren, United Kingdom
17:15 - 17:30
Development and validation of an artificial intelligence based algorithm for the selection of an optimal stimulation protocols in IVF patients
Nuria Correa, Spain
17:30 - 17:45
Optimization of prediction models for live birth and miscarriage rate in intrauterine insemination between homologous and frozen donor semen
María José Soriano, Spain
17:45 - 18:00
Comparison of machine learning models for the prediction of live birth following IVF treatment: an analysis of 463,669 cycles from a national database
Ioannis Sfontouris, Greece

17:00 - 18:00
Session 54: Biomarkers for male fertility
Chairmen
Lars Björndahl, Sweden
Anna Blazquez, Spain
17:00 - 17:15
Afamin, a novel human vitamin E-binding glycoprotein, as a marker of male infertility.
Rocio Nunez - Calonge, Spain
17:15 - 17:30
combining RNA-seq and proteomic profiling in cryopreserved human sperm exposed to sublethal stress: new biomarkers for stress-tolerance in sperm
Maryam Hezavehei, Iran
17:30 - 17:45
Attenuation of peroxiredoxin activity induce apoptosis in seminal plasma of men with idiopathic male infertility: striking the chord for evaluation of a novel biomarker
Pratip Chakraborty, India
17:45 - 18:00
Seminal plasma cell-free mitochondrial DNA copy number is associated with human semen quality
Yuezhou Chen, China

17:00 - 18:00
Session 55: Female and male fertility preservation
Chairmen
Chairman to be announced
Clara Gonzalez Llagostera, Spain
17:00 - 17:15
Freezing ovarian tissue and simultaneously obtaining an average of 8 mature oocytes without ovarian stimulation - is it a reality?
Dmitry Nikiforov, Italy
17:15 - 17:30
Recovery of ovarian function after chemotherapy for Hodgkin lymphoma is limited by age, not pretreatment ovarian reserve
Richard Anderson, United Kingdom
17:30 - 17:45
Recombinant AMH prevents primordial follicle loss and long term fertility alteration in cyclophosphamide treated mice
Charlotte Sonigo, France
17:45 - 18:00
Organotypic culture of fresh and cryopreserved-thawed human prepubertal and pubertal testis
Joana Portela, The Netherlands

17:00 - 18:00
Session 56: Biology of oocyte and cumulus complex
Chairmen
Signe Altmäe, Spain
Gorka Barrenetxea Ziarrusta, Spain
17:00 - 17:15
Mitochondrial DNA sequence variation in human oocytes by single-cell mtDNA sequencing
Qiao Zeng, China
17:15 - 17:30
Transcriptional profile of tubulin post translational modification (PTM) enzymes throughout human oocyte meiotic progression in vivo and in vitro
Paraskevi Karamtzioti, Spain
17:30 - 17:45
Dual trigger vs. hCG for final oocyte maturation. A prospective randomized controlled, double blinded study: preliminary results
Jigal Haas, Canada
17:45 - 18:00
Anti-Müllerian hormone promotes granulosa cell proliferation in the preantral-to-early antral follicles, but induces granulosa cell apoptosis during the subsequent follicular development, in the primate ovary
Jing Xu, U.S.A.

17:00 - 18:00
Session 57: Approaching the clinic: Stem cells treatments for infertility
Chairmen
Mieke Geens, Belgium
Cristina Eguizabal, Spain
17:00 - 17:15
Autologous mitochondrial transfer as a complementary technique to ICSI to improve oocyte and embryo quality in IVF patients. A Randomized Pilot Study.
Elena Labarta Demur, Spain
17:15 - 17:30
3D Architecture of endometrial glands in relation to stem cell organisation
Dharani Hapangama, United Kingdom
17:30 - 17:45
Human pluripotent stem cell-derived cells expressing functional follicle-stimulating hormone receptor (FSHR) - a tool for functional studies and disease modeling
Karolina Lundin, Finland
17:45 - 18:00
A novel two-step transplantation procedure using adipose tissue-derived stem cells increases follicle survival by boosting angiogenesis in xenografted frozen-thawed human ovarian tissue
Diego D. Manavella I., Belgium

17:45 - 18:45
Product theatre

09:00 - 10:00
Implantation and early pregnancy
09:00 - 09:15
Increased NK-cell subsets with inhibitory cytokines and surface receptors in patients with recurrent miscarriage
Ruben-J. Kuon, Germany
09:15 - 09:30
Changes in human chorion gonadotropin as a predictor of live birth outcome among Danish women with recurrent pregnancy loss.
Selma Landersø, Denmark
09:30 - 09:45
The uterine cavity in patients with recurrent pregnancy loss (RPL)
Laerke Heidam Juul Andersen, Denmark
09:45 - 10:00
Frozen Embryo Transfer Protocols: Which one is best?
Jolly Joy, United Kingdom

10:00 - 11:00
Reproductive epidemiology, socio-cultural aspects and health economy
10:00 - 10:15
Follicular fluid concentrations of phthalate metabolites and early reproductive outcomes among women undergoing in vitro fertilization
Na Guo, China
10:15 - 10:30
The association between the number of oocytes retrieved for IVF, perinatal outcomes and obstetric complications.
Åsa Magnusson, Sweden
10:30 - 10:45
Dizygotic multiple pregnancy, Dutch trends over two decades from 1995 through 2015
Tamar Konig, The Netherlands
10:45 - 11:00
The sex ratio in twins and the influence of gender mix in twins on gestational age, birth weight and perinatal mortality
Birgit Decommer, Belgium

10:00 - 11:00
Reproductive surgery
10:00 - 10:15
Robot-assisted myomectomy may improve pregnancy rates after surgery
Stephanie Huberlant, France
10:15 - 10:30
Clinical pregnancy outcome of secondary infertility treated by transvaginal repair of previous cesarean scar defect
Wujiang Liu, China
10:30 - 10:45
Skilled reproductive surgeons may ensure better outcomes in infertile patients
Virginia Vargiu, Italy
10:45 - 11:00
Who is at risk of endometrial cavity breach at laparoscopic myomectomy?
Kuhan Rajah, United Kingdom

11:00 - 12:00
Psychology and counselling 
11:00 - 11:15
Obsessive symptoms and the need of gamete donation as predictors of treatment dropout in infertile patients
Ludmila Jurkowski, Argentina
11:15 - 11:30
The evaluation of patients’ experience with manual vacuum aspiration: Comparison with other methods of miscarriage managements and infertility procedures
Wing Ching Cheung, Hong Kong
11:30 - 11:45
Fertility- and early menopause-related information needs of young breast cancer survivors
Ellen Marie Sparidaens, The Netherlands
11:45 - 12:00
A pregnancy loss in the first fertility treatment is a postitive predictor of birth in the following treatment
Maria Christine Krog, Denmark

11:00 - 12:00
Safety and quality of ART therapies
11:00 - 11:15
The effect of the underlying type of infertility on placental-mediated adverse outcomes for patients that used IVF: a population-level study
Andrea Lanes, Canada
11:15 - 11:30
Letrozole and risk of major congenital malformations: a systematic review and meta-analysis
Jyotsna Pundir, United Kingdom
11:30 - 11:45
Anti-Mullerian hormone level decrease and efficacy of ART programs in HIV-infected women
Fatima Selimova, Russia C.I.S.
11:45 - 12:00
Perinatal outcomes in children born after IVF using a GnRh-agonist protocol versus a GnRh antagonist protocol: a Catalan cohort study based on 4562 newborns
Mar Vidal Segui, Spain

12:00 - 13:00
Female fertility
Signe Altmäe, Spain
12:00 - 12:15
Dynamic culture of human ovarian tissue in a perfusion flow-through bioreactor enhances follicle progression as compared to static culture in gas-permeable dishes
Riccardo Talevi, Italy
12:15 - 12:30
An increase of intracellular cyclic AMP improves mitochondrial function of bovine immature oocytes
Shu Hashimoto, Japan
12:30 - 12:45
Granulosa cells provide elimination of apoptotic oocytes through unconventional autophagy-assisted phagocytosis.
Marina Yefimova, Russia C.I.S.
12:45 - 13:00
Unravelling the molecular pathways responsible for sex determination in humans
Jasin Taelman, Belgium

12:00 - 13:00
Reproductive (epi)genetics
12:00 - 12:15
Segmental aneuploidy (SA) in oocytes and preimplantation embryos
Cristina Albanese, Italy
12:15 - 12:30
Higher resolution aneuploidy screening with targeted NGS may increase the pool of transferrable embryos despite inclusion of segmental and mosaic range diagnostic categories
Paul Pirtea, U.S.A.
12:30 - 12:45
Genomic profiling of spermatogenetic function in azoospermic men
Brandon Chin, U.S.A.
12:45 - 13:00
Reassessing the prevalence of aneuploidy in sperm retrieved from different levels of the male genetic tract
Stephanie Cheung, U.S.A.

14:00 - 15:00
Female infertility
14:00 - 14:15
Outcome of Progestin-primed ovarian stimulation protocol vs. ultra-long protocol in patients with a first IVF/ICSI cycle: a randomized clinical trail
Xi Qianwen, China
14:15 - 14:30
Frozen-thawed embryos generated from a successful fresh IVF cycles have higher potential for favorable outcome than frozen-thawed embryos obtained from unsuccessful fresh cycles
Alex Simon, Israel
14:30 - 14:45
Fresh or vitrified: comparing the number of oocytes necessary to achieve reproductive success in egg donation programme
Hana Visnova, Czech Republic
14:45 - 15:00
Antibodies to chlamydial heat shock protein 60 kDa in sera and follicular fluid of women undergoing IVF
Valeria Muller, Russia C.I.S.

14:00 - 15:00
Stem cells
14:00 - 14:15
The synergetic effects of multiwall carbon nanotubes/poly lactic acid 3-D composite nanofibrous scaffold containing naringenin on spermatogenesis
Hossein Eyni Seen, Iran
14:15 - 14:30
Feasibility of CRISPR-Cas9 on the human sperm cell
Diane Choi, U.S.A.
14:30 - 14:45
Intrauterine infusion of autologous peripheral blood mononuclear cells in frozen blastocyst transfer improves clinical outcome and metabolomic profile in repeated implantation failure- A pilot study
Baidyanath Chakravarty, India
14:45 - 15:00
Proteomic profiling of the exosomes released by endometrial mesenchymal stem cells: possible relations with embryo development and implantation
Federica Marinaro, Spain

15:00 - 16:00
Andrology
15:00 - 15:15
Male accessory sexual glands secretion as a potential predictor of fertilization in conventional IVF
Ignacio de Zuñiga, Argentina
15:15 - 15:30
Changes in ultrasonographic (US) images of the seminiferous tubules during gonadotropin replacement therapy in men with hypogonadotropic hypogonadism
Shoichi Nariyoshi, Japan
15:30 - 15:45
The impact of sperm chromatin condensation and ploidy on IVF/ICSI outcome
Leandros Lazaros, Greece
15:45 - 16:00
Assessment of the impact of CryoFlex tubing on sperm cryopreservation outcome.
Tamer Said, Canada

15:00 - 16:00
Male and female fertility preservation
15:00 - 15:15
IVM after vitrification induces alterations of maturation rates and deleterious effects on actin and tubulin architecture of human oocytes
Aïcha Metchat, France
15:15 - 15:30
Assessment of a sensitive and specific method to detect Ewing sarcoma minimal residual disease in testicular and ovarian tissue by RT-qPCR
Laure Chaput, France
15:30 - 15:45
Texture profile analysis reveals a stiffer ovarian cortex after testosterone therapy
Chloe De Roo, Belgium
15:45 - 16:00
Towards fertility preservation for prepubertal boys – The role of gonadotrophins on functional maturation of Leydig and Sertoli cells in immature human testis xenografts
Rod Mitchell, United Kingdom

16:00 - 17:00
Endometriosis, endometrium and fallopian tube, and benign disorders of the endometrium and fallopian tube 
16:00 - 16:15
Naturally occurring endometriosis in the cynomolgus macaque: effects of analgesics on pain-related behavior and brain activation
I. Hayashi, Japan
16:15 - 16:30
The human fallopian tube vs endometrium: can differences in function and steroid hormone receptor expression be explained by differential hormone responsiveness?
Alison Maclean, United Kingdom
16:30 - 16:45
A specific serum cytokines profile determines disease phenotype in adenomyosis-affected women
Mathilde Bourdon, France
16:45 - 17:00
Aberrant ER stress induction in response to progesterone enhances endometriotic stromal cell invasiveness.
DooSeok Choi, Korea, South

16:00 - 17:00
Ethics and law 
16:00 - 16:15
A comparative analysis of marketing materials used to recruit egg donors in Belgium, Spain and the United Kingdom
Veerle Provoost, Belgium
16:15 - 16:30
Attitudes and opinions towards gestational surrogacy among physicians working within reproductive medicine and obstetrics in Sweden.
Kjell Wånggren, Sweden
16:30 - 16:45
Ethical evaluation of informing relatives of premature menopause (PM) patients
Mohammad Rasekh, Iran
16:45 - 17:00
Reproductive Endocrinology Infertility (REI) specialists’ utilization and attitudes towards expanded carrier screening for oocyte donors
S.R. Lindheim, U.S.A.

17:00 - 18:00
Embryology
17:00 - 17:15
Does blastocyst re-expansion one hour post-warming predict clinical pregnancies?
Chloe Shaw Jackson, Belgium
17:15 - 17:30
Correlation between euploid blastocysts expansion/morphology and clinical outcomes in cycles with single frozen embryo transfer
Mariana Nicolielo, Brazil
17:30 - 17:45
Male Factor is the most important factor influencing the frequency of unequal direct cleavage events as visualized by time-lapse during early embryo development
Stephen Davies, Greece
17:45 - 18:00
Let-7b microRNA modulates attachment of trophoblastic cells and integrin β3 expression of endometrial cells
Jihyun Kim, Korea, South

17:00 - 18:00
Reproductive endocrinology
17:00 - 17:15
iTRAQ-based proteomic profile of ovarian granulosa cells from women with PCOS undergoing IVF/ICSI
Huang Zhongying, China
17:15 - 17:30
Comparative analysis of structural differences of Ovaleap and GONAL-f: site-specific glycosylation mapping and cell signaling activation
Monica Lispi, Italy
17:30 - 17:45
Cross-talk between Bcl2l10 and Aurka in regulation of meiotic spindle assembly
Su-Yeon Lee, Korea, South
17:45 - 18:00
Effect of resveratrol and metformin on ovarian reserve and ultrastructure in PCOS: An experimental study
Selenay Furat Rencber, Turkey