Main programme

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Monday 03 July 2017

08:30 - 09:30
Session 01: Keynote session
Chairmen
Johannes Evers, The Netherlands
Kersti Lundin, Sweden
08:30 - 09:00
Human Reproduction keynote lecture - Autologous cell therapy with CD133+ bone marrow-derived stem cells for refractory Asherman's syndrome and endometrial atrophy: a pilot cohort study
Carlos Simon Valles, Spain
09:00 - 09:30
Non-invasive prenatal testing (NIPT) - state of the art
Dennis Lo, Hong Kong

09:30 - 10:00
Coffee break (in the exhibit hall)

10:00 - 11:30
Session 02: Novel ideas in embryology
Chairmen
Daniela Nogueira, France
Greta Verheyen, Belgium
10:00 - 10:15
Influence of opening the incubator on morphokinetics in mouse embryos
Volker Ziller, Germany
10:15 - 10:30
Image analysis of human embryos grown in vitro as a new non-invasive tool to determine embryo health
Anna Leida Mölder, United Kingdom
10:30 - 10:45
Study of embryo surface variation and contraction pattern as potential predictors of embryo chromosomal content
Xavier Viñals, United Kingdom
10:45 - 11:00
Oliana Strings: Perivitelline threads that originate from corona radiata cells and cause fragmentation in human embryos
Oriol Oliana Membrado, United Kingdom
11:00 - 11:15
Does the extent of blastocyst hatching at time of trophectoderm biopsy affect PGD clinical outcome?
Yaser Dajani, United Kingdom
11:15 - 11:30
Complete zona pellucida removal facilitates embryo attachment and outgrowth by upregulating the integrin α5 and β1 expression in human blastocysts: in vitro outgrowth model
Kenji Ezoe, Japan

10:00 - 11:30
Session 03: Refining protocols
Chairmen
Frank J. Broekmans, The Netherlands
Isabelle Marie Streuli, Switzerland
10:00 - 10:15
Ovarian stimulation in IUI cycles in couples with unexplained subfertility: follicle stimulating hormone (FSH) or clomiphene citrate (CC)?
Noor Danhof, The Netherlands
10:15 - 10:30
A randomized controlled trial of intrauterine insemination with clomiphene citrate stimulation compared with expectant management for women with unexplained infertility (The TUI study)
Cindy M. Farquhar, New Zealand
10:30 - 10:45
Intrauterine insemination: does timing matter? A multicenter randomised controlled trial
Odette Rijsdijk, The Netherlands
10:45 - 11:00
Anovulatory women not conceiving after six ovulatory cycles with clomiphene citrate – should we switch to gonadotrophins and/or add IUI? A 2 by2 factorial RCT
Nienke Weiss, The Netherlands
11:00 - 11:15
Corifollitropin alfa followed by hp-HMG versus recombinant FSH in young poor ovarian responders: a multicenter randomized controlled clinical trial
Panagiotis Drakopoulos, Belgium
11:15 - 11:30
Letrozole step-up protocol: the effect of a novel superovualtion induction protocol to enhance pregnancy rate in a couple with unexplained infertility undergoing intrauterine insemination
Ahmed Galal, Egypt

10:00 - 11:30
Session 04: The role of genes testis structure in male infertility
Chairmen
Stefan Schlatt, Germany
Michael Zitzmann, Germany
10:00 - 10:15
Blood-testis barrier organization in a prepubertal and peripubertal boys’ cohort: correlation with Sertoli cell maturation, clinical puberty and testicular anatomopathology
Francesca De Michele, Belgium
10:15 - 10:30
Gradient system for testicular organoids generation – a novel system to model germ to somatic cell association in vitro
João Pedro Alves Lopes, Sweden
10:30 - 10:45
In vitro re-assembly of human primary testicular cells into seminiferous cord-like structures
Mina Mincheva, Germany
10:45 - 11:00
Oxidation reduction potential: a valuable tool for male fertility evaluation
Ahmad Majzoub, Qatar
11:00 - 11:15
High prevalence of PLCz mutations among cases of failed oocyte activation, but not anomalous fertilization, after IVF/ICSI
Montse Barragan, Spain
11:15 - 11:30
Klinefelter syndrome and fertility – impact of X-chromosomal inheritance on spermatogenesis
Sebastian Franik, Germany

10:00 - 11:30
Session 05: Improving implantation
Chairmen
Siobhan Quenby, United Kingdom
Petya Chaveeva, Bulgaria
10:00 - 10:15
Evidence base for investigation and management for unexplained Recurrent Implantation Failure (RIF): A systematic review and meta-analysis
Emily Wade, United Kingdom
10:15 - 10:30
Improving the pre-conceptual uterine natural killer (uNK) cell test to predict pregnancy outcome in recurrent miscarriage
Mariam Lokman, United Kingdom
10:30 - 10:45
Acetylsalicylic acid for prevention of pregnancy loss: a randomized trial
Lennart Blomqvist, Sweden
10:45 - 11:00
A placebo-controlled, randomized, double-blind study of pregnancy and live birth rates after single oral administration of a novel oxytocin antagonist, nolasiban, prior to embryo transfer.
Herman Tournaye, Belgium
11:00 - 11:15
High-quality human preimplantation embryos actively influence endometrial stromal cell migration
Robbert Berkhout, The Netherlands
11:15 - 11:30
Endometrial function in women with diabetes: role of the hexosamine biosynthetic pathway (HBP)
Joanne Muter, United Kingdom

10:00 - 11:30
Session 06: Developments in genetic testing
Chairmen
Claudia Spits, Belgium
Giuditta Filippini, Switzerland
10:00 - 10:15
Spent blastocyst media and blastocoel fluid are not reliable DNA sources for preimplantation genetic diagnosis of aneuploidies and monogenic disorders
Valeria Romanelli, Italy
10:15 - 10:30
Development and application of a novel strategy to explore blastocoel fluid and spent culture media as a source of embryonic DNA
Dhruti Babariya, United Kingdom
10:30 - 10:45
Non-Invasive PGS reveals the existence of complementary aneuploidy between DNA obtained from trophectoderm biopsy versus DNA in spent culture medium in the same embryo
Maria Vera Rodriguez, Spain
10:45 - 11:00
Superiority of array Comparative Genome Hybridization (aCGH) over Next Generation Sequencing (NGS) for PGD for reciprocal translocations
Tomas Escudero, U.S.A.
11:00 - 11:15
Development, validation and first clinical application of a novel ultra-rapid comprehensive chromosome screening technique utilising an array based nano scale quantitative DNA amplification technology
Katharina Spath, United Kingdom
11:15 - 11:30
A novel next generation sequencing (NGS)-based comprehensive chromosome screening (CCS) platform that provides accurate copy number and genotyping in parallel from a single trophectoderm biopsy
Diego Marin, U.S.A.

10:00 - 11:30
Session 07: Long-term consequences in ART
Chairmen
Arianna D'Angelo, United Kingdom
Paul Bischof, Switzerland
10:00 - 10:15
How to compare outcomes of IVF/ICSI patients with different backgrounds and treated by different regimens
Zdravka Veleva, Finland
10:15 - 10:30
Effect of culture medium on cardiovascular characteristics of 9-year-old IVF/ICSI singletons
Heleen Zandstra, The Netherlands
10:30 - 10:45
Assisted reproductive technology might affect the growth of children: a prospective cohort study on 3,509 babies
TOMOYA HASEGAWA, Japan
10:45 - 11:00
Effect of parental and treatment aspects of IVF/ICSI on perinatal outcomes: a nationwide study of IVF/ICSI singletons born in The Netherlands between 2000 and 2011
Martina Pontesilli, The Netherlands
11:00 - 11:15
Weight and waist circumference of IVF children at the age of 9 years still affected by embryo culture medium
Heleen Zandstra, The Netherlands
11:15 - 11:30
The number of oocytes retrieved during IVF: a balance between efficacy and safety
Åsa Magnusson, Sweden

11:45 - 13:00
Industry sponsored symposium

11:45 - 12:45
Session 08: Ovarian rejuvenation: for real or just a dream?
Chairmen
Luca Gianaroli, Italy
Susana M. Chuva de Sousa Lopes, The Netherlands
11:45 - 12:15
Mitochondrial transfer- can it improve oocyte quality?
Jacques Cohen, U.S.A.
12:15 - 12:45
Improving ovarian response through ovarian tissue activation
Kazuhiro Kawamura, Japan

11:45 - 12:45
Session 09: Data reporting session
Chairmen
Joep Geraedts, The Netherlands
Markus S. Kupka, Germany
11:45 - 12:15
Data from the ESHRE PGD Consortium
Martine De Rycke, Belgium
12:15 - 12:45
Results of ESTEEM: an RCT to test preimplantation genetic testing for aneuploid
Karen Sermon, Belgium

11:45 - 12:15
Session 10: Fertility Society of Australia Exchange Lecture
Chairmen
Michael G. Chapman, Australia
Richard Anderson, United Kingdom
11:45 - 12:15
New strategies for ovarian preservation during cancer treatment: Elimination of PUMA confers protection against chemotherapy-mediated oocyte loss
Quynh-nhu Nguyen, Australia

11:45 - 12:45
Session 11: Paramedical invited session: Sperm messaging - what's the story?
11:45 - 12:15
Genetic screening in cases of extreme poor spermatogenesis
Liliana Ramos, The Netherlands
12:15 - 12:45
Evaluating oocyte activation potential of sperm using calcium pattern analysis
Bjorn Heindryckx, Belgium

13:00 - 14:00
Industry sponsored session

13:00 - 14:00
Lunch break (in the exhibit hall)

14:00 - 15:15
Industry sponsored symposium

14:00 - 15:00
Session 12: The science and ethics behind germline genome editing
Chairmen
Guido Pennings, Belgium
Joyce Harper, United Kingdom
14:00 - 14:30
Gene editing in the human germ line - risks and possibilities
Robin Lovell-Badge, United Kingdom
14:30 - 15:00
Should we edit the genomes of our future children?
Stephen Wilkinson, United Kingdom

14:00 - 15:00
Session 13: Recent developments in ovarian (hyper) stimulation and ovulation induction
Chairmen
Roy Homburg, United Kingdom
Bart C.J.M. Fauser, The Netherlands
14:00 - 14:30
Individualised ovarian stimulation for IVF: balancing cumulative outcome, safety, burden and costs
Anders Nyboe Andersen, Denmark
14:30 - 15:00
The evolution of treatment approaches in PCOS: management of ovulation and metabolism
Richard Anderson, United Kingdom

14:00 - 15:00
Session 14: Debate: Deep endometriosis: to operate or not in infertile women
Chairmen
Gregoris Grimbizis, Greece
Michael D. Mueller, Switzerland
14:00 - 14:30
Pro
Horace Roman, France
14:30 - 15:00
Con
François Golfier, France

14:00 - 15:00
Session 15: Paramedical session - Listening to the patient
Chairmen
Helen J. Kendrew, United Kingdom
Eline Dancet, Belgium
14:00 - 14:15
Endometriosis: Why am I feeling pain?
Uny Monique, Switzerland
14:15 - 14:30
Follow-up of oocyte donors ten years after donation: what we are doing well and what we could improve
mireia perul, Spain
14:30 - 14:45
Patient-friendly insemination with homologous and donor sperm positively influences clinical pregnancy rates
Hilde Bijnens, Belgium
14:45 - 15:00
Are nurse-led consultations of benefit to patients? Evidence of effectiveness from a UK clinic specialising in IUI
Bryan Woodward, United Kingdom

15:15 - 16:30
Session 16: Optimizing the embryo environment
Chairmen
Basak Balaban, Turkey
Susanna Jamina Apter, Sweden
15:15 - 15:30
Ultra-low (2%) oxygen tension significantly improves human blastocyst development and quality
Alice Ferrieres-Hoa, France
15:30 - 15:45
The composition of human preimplantation embryo culture media and their stability during storage and culture
Majid Tarahomi, The Netherlands
15:45 - 16:00
Potential contamination of fresh embryo cell culture medium with cell free DNA
Amael Petiton, France
16:00 - 16:15
A novel three-dimensional environment for human blastocyst development up to 10 days post-fertilization
Fatemeh Arjmandteymouri, Iran
16:15 - 16:30
Cell allocation patterns during pre-implantation embryo development are not perturbed by blastomere removal in mouse and bovine embryos
Lessly Pilar Sepulveda Rincon, United Kingdom

15:15 - 16:30
Session 17: Life-style and preparation for IVF
Chairmen
Aila Tiitinen, Finland
Chairman to be announced
15:15 - 15:30
Effect of a lifestyle intervention in obese infertile women on cardiometabolic health and quality of life: results of a randomised controlled trial
Vincent Wekker, The Netherlands
15:30 - 15:45
Weight reduction intervention for obese infertile women prior to In vitro fertilisation; a randomised controlled trial
Snorri Einarsson, Iceland
16:00 - 16:15
A concise infertility work-up reduces pregnancy chances: a historical cohort study
Jozefien Hamilton, The Netherlands
16:15 - 16:30
Maternal obesity programs transgenerational mitochondrial dysfunction via the original, maternal oocytes, not due to exposure during gestation
Kelle Moley, U.S.A.

15:15 - 16:30
Session 18: Updates on PCOS
Chairmen
Georg Griesinger, Germany
Alessandro Santi, Switzerland
15:15 - 15:30
Follicular ADAMTS-1 and aggrecan in polycystic ovary syndrome (PCOS)
Esra Nur Tola, Turkey
15:30 - 15:45
Randomized controlled trial of combined lifestyle and herbal medicine in women with polycystic ovary syndrome
Susan Arentz, Australia
15:45 - 16:00
Comparative effectiveness of 9 ovulation-induction therapies on patients with clomiphene citrate-resistant polycystic ovary syndrome: a network meta- analysis
Yiping Yu, China
15:45 - 16:00
Impact of dramatic weight loss linked to bariatric surgery on ovarian response and pregnancy rates after in vitro fertilization (IVF): a case-control study
Véronique Grzegorczyk Martin, France
16:00 - 16:15
Factors associated with gestational weight gain and birth weight in women with PCOS: a controlled study
Richard Legro, U.S.A.
16:15 - 16:30
Healthcare providers’ knowledge, diagnosis and management of polycystic ovary syndrome (PCOS) in Europe, North America and internationally
Melanie Gibson-Helm, Australia

15:15 - 16:30
Session 19: Cryopreservation of oocytes and embryos
Chairmen
Sophie Debrock, Belgium
Maria Jose De Los Santos, Spain
15:15 - 15:30
Impact of post-warming culture duration on clinical outcomes of vitrified good-quality blastocyst transfers: a prospective randomized study
Charlène Herbemont, France
15:30 - 15:45
Laser-assisted hatching improves clinical outcomes of top grade, vitrified–warmed blastocysts developed in high prognosis oocyte donation cycles: a prospective randomized study
Yannis Panagiotidis, Greece
15:45 - 16:00
Clinical outcomes of blastocysts vitrified-warmed using a new semi-automated vitrification system are comparable to the gold standard open vitrification method
Natalie Hobson, Australia
16:00 - 16:15
Laser assisted hatching before embryo transfer improves the clinical outcome in cases with vitrified oocytes from an egg donor cryobank: a prospective, control, randomized study
Achilleas Papatheodorou, Greece
16:15 - 16:30
Live birth after frozen-thawed blastocyst transfer is correlated with the day of blastocyst expansion
Khaled Pocate, France

15:15 - 16:30
Session 20: Different types of pluripotent stem cells
Chairmen
Bjorn Heindryckx, Belgium
Cristina Eguizabal, Spain
15:15 - 15:30
Comprehensive cell-surface protein profiling identifies novel markers of human naïve and primed pluripotent states
Sarita Panula, Sweden
15:30 - 15:45
Wnt inhibition during hESC culture provides an improved pluripotent state starting point for directed differentiation
Jasin Taelman, Belgium
15:45 - 16:00
Origins of human embryonic stem cell fate: role of the post inner cell mass intermediate
Mina Popovic, Belgium
16:00 - 16:15
Mitochondrial protein acylglycerol kinase orchasdrates stem cell pluripotency
Yanlin Ma, China
16:15 - 16:30
Two live birth after Stem cell ovarian auto-transplantation in Poor Responder women
Sonia Herraiz, Spain

15:15 - 16:30
Session 21: Reproduction after cancer treatment
Chairmen
Kirsten Louise Tryde Macklon, Denmark
Alain Chanson, Switzerland
15:15 - 15:30
Long-term effect of childhood cancer treatment on ovarian function markers: final results of the DCOG-LATER VEVO study
Annelies Overbeek, The Netherlands
15:30 - 15:45
Pregnancy after cancer in girls and women in Scotland: a population-based analysis
Richard Anderson, United Kingdom
15:45 - 16:00
Fertility preservation by oocyte vitrification or ovarian cortex cryopreservation. A prospective cohort study
César Díaz-García, Spain
16:00 - 16:15
Severely decreased spermatogonial quantity after chemotherapy with alkylating agents in prepubertal boys
Ieva Masliukaite, The Netherlands
16:15 - 16:30
Assessment of testicular sperm extraction (TESE) and intracytoplasmic sperm injection (ICSI) in couples with post chemotherapy non-obstructive azoospermia (NOA)
Nao Tsuji, Japan

16:00 - 17:00
Industry sponsored session
Insulin sensitizers and PCOS: Physiology and therapeutic use of inositols
Chairman
S. Benvenga, Italy
John E. Nestler, U.S.A.

16:30 - 17:00
Coffee break (in the exhibit hall)

17:00 - 18:15
Industry sponsored symposium
Transforming fertility management
Chairmen
Bart C.J.M. Fauser, The Netherlands
Marc Germond, Switzerland
Fibroids and fertility: From present to future
Jacques Donnez, Belgium
Safeguarding fertility: Why the debate?
Michaël Grynberg, France
Preventing transmission of abnormal mitochondrial DNA
Alison Murdoch, United Kingdom

17:00 - 18:00
Session 22: Has transcriptome analysis of oocytes and embryos run its course? Single cell omics
Chairmen
Anna Veiga, Spain
Ursula Eichenlaub-Ritter, Germany
17:00 - 17:30
Single-cell proteomics of human oocytes
Jeroen Krijgsveld, Germany
17:30 - 18:00
Deciphering developmental processes from single-cell transcriptomes
Paul Robson, U.S.A.

17:00 - 18:00
Session 23: Are microwave food containers, water bottles and soft drink cans making you infertile?
Chairmen
Jackson Kirkman-Brown, United Kingdom
David Mortimer, Canada
17:00 - 17:30
Plasticizers and male fertility
Richard Sharpe, United Kingdom
17:30 - 18:00
Plastics and miscarriage
Ruth Lathi, U.S.A.

17:00 - 18:00
Session 24: Changing the life course for PCOS
Chairmen
Laure C. Morin - Papunen, Finland
Adam Balen, United Kingdom
17:00 - 17:30
PCOS in adolescence-to diagnose or not and future fate
Kathy Hoeger, U.S.A.
17:30 - 18:00
Is there a need to increase PCOS awareness?
Helena Teede, Australia

17:00 - 18:00
Session 25: Paramedical session - Laboratory - Increasing performance
Chairmen
Yves Guns, Belgium
Cecilia Westin, Sweden
17:00 - 17:15
A time-lapse incubator is a superior incubator for excellent quality blastocyst embryo development compared to a conventional incubator
Sofie Ellegiers, Belgium
17:15 - 17:30
Effect of accurate temperature regulation during incubation on embryo quality after ICSI: a prospective sibling oocyte study on two incubation temperatures (36.6°C or 37.1°C)
Ronny Janssens, Belgium
17:30 - 17:45
Key performance indicators (KPIs-Score) based on clinical and laboratorial parameters can establish benchmarks for internal quality control (IQC) in an embryo cryopreservation programme
Ana Lucia Mauri, Brazil
17:45 - 18:00
A quick, easy and effective sperm wash procedure for HCV+ and HIV+ patients
Jonas De Creus, Belgium