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Frequency of high SDF values among men with unexplained infertility
SCD ≥ 30%
Conventional semen parameters within normal range (WHO 2010)
No abnormalities found on physical exam or history
17%
Normal semen analysis results (WHO)
N=387; Androfert: 2016-2018
High SDF
Esteves, 23
Recurrent Pregnancy Loss
SDF rates (TUNEL) higher in RPL couples than controls
36.8% vs. 9.4%; P<0.001 17.1% vs. 10.2%; P=0.01 18.8% vs. 12.8%; P<0.001
Bareh et al, Fertil Steril 2016 Zidi-Jrah et al, Fertil Steril 2016 Carlini et al. RBM Online 2017
DFI of 26% (SCSA) discriminate couples with RPL from controls: 73% sensitivity, 90% specificity, 83% accuracy
Kumar et al, JARG 2012 Positive association between number of pregnancy
loss events and DFI (r=0.20; P<0.05)
Carlini et al, RBM Online 2017
Esteves, 24
Esteves, 24
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