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Algorithm for the clinical utility of sperm DNA fragmentation in assisted reproductive treatments
+ Counselling regarding the expected outcomes with each ART modality
High SDF
Unexplained infertility Recurrent Miscarriage Recurrent IUI failure Recurrent IVF failure Recurrent ICSI failure High SDF
Majzoub et al. Transl Androl Urol 2017 Esteves, 33
IUI
IVF
ICSI
High SDF
ICSI
Testicular sperm ICSI
Conditions were sperm DNA fragmentation (SDF) is indicated IUI: intrauterine insemination
IVF: In vitro fertilization
ICSI: intracytoplasmic sperm injection
3 4
The use of testicular sperm in preference over ejaculated sperm in IVF/ICSI failure will be discussed in next talk entitled
“Testicular or ejaculated sperm (when both are available) in oligozoospermia and ICSI failure”
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PRECONGRESS COURSE 01 I VIENNA, AUSTRIA – 23 JUNE 2019 41