Page 68 - ESHRE2019

Expected effects of antioxidants
Effect on:
• Semen characteristics (±) • Count(±)
• Motility (±)
• Morphology(±)
• Sperm DNA Fragmentation (+++) • Embryo Development (++)
• Natural pregnancies, IUI • IVF/ICSI
• Miscarrriage
When sperm DNA is fragmented!
Effect of antioxidants in absence of oxidative stress???
In clinical practice
• Detecting risk factors for increased sperm DNA fragmentation
• Measuring sperm DNA fragmentation index
• Eliminating risk factors
• Antioxidant treatment
• Checking DNA fragmentation index before ART
• Selecting sperms with lowest DFI for ART.
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