Page 106 - ESHRE2019

Automatic annotations and computer analysis added to cleavage embryos?
Implantation Rate KID (p=0,017)
60%
50%
40%
30% 24% 20%
53,91%
12345
Aparicio‐Ruiz. et al. ASRM 2018.
52,63%
45,68%
39,02%
Xtend
Category
1
230
2
133
3
81
4
41
5
29
Total
514
10% 0%
Evolution of invasive methods for embryo assessment (PGT); increasing the knowledge of chromosome dynamics
1991-1995
PCR
FI SH
2-12 chromosomes
Mostly day-3 biopsies 2 blastomeres lear ning cur ves
2008
Array Comparative Genom ic Hybridization (aCGH)
2010
Quantitative polymerase chain reaction (qPCR)
2012
Single-nucleotide polymorphism (SNP) microarray
2014
Next-Generation Sequencing (NGS)
Analysis of a identified single gene disease
24 chromosomes
+
Mito DNA; mutations
24 chromosomes
104
101