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From meiotic to mitotic chromosome segregation
Clift and Schuh, 2013
Zygote (anaphase) Zygote (anaphase)
Aberrant cleavage occurs at early stage ‐ Direct (trichotomous) cleavage ‐
DC‐1
Direct cleavage (DC) of 1‐ to 3‐cell (Rubio et al., 2012)
• 14% of all embryos
• 1.2% implantation rate (pregnancies?) DC can also occur at later stages
DC‐2 DC‐3
Classical morphology is unable to detect DC embryos that are often selected for transfer
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