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Asymmetric meiotic cell divisions in mouse oocytes
4C
immature oocyte
Actomyosin cortical domain
meiosis I (MI)
1st polar body
2C
MII (mature oocyte)
2nd polar body
+ 1C 1C
zygote
I. How does the meiosis I spindle move to the cortex?
II. How does meiosis II spindle maintain a subcortical localization?
III. How does meiosis II spindle rotate to accomplish cell division?
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PRECONGRESS COURSE 02 I VIENNA, AUSTRIA – 23 JUNE 2019 11