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There is not enough evidence to recommend testing for any blood or urine biomarker in clinical practice
2016
2015
17
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Weaknesses of the published studies in biomarker discovery
Small case and control groups.
Studies performed in non‐target population.
Insufficient characterization of case and control groups
(type and stage of endometriosis, menstrual phase, hormonal therapy, age, BMI).
Nonstandardized procedures of blood collection, storage and processing. Inappropriate statistical analyses.
No data about diagnostic accuracy.
Lack of validation in independent data sets and in other populations.
18
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PRECONGRESS COURSE 03 I VIENNA, AUSTRIA – 23 JUNE 2019 139