Page 167 - ESHRE2019

Pain improvement after laparoscopy
Favours No Surgery Favours Surgery
Jacobson et al, Cochrane Reviews 2010
Response to surgical therapy and symptom recurrence after treatment cessation
No reduction in pain symptoms
Persistence of pain symptoms remaining after surgery
Recurrent symptoms
Recurrent surgery
Change in VAS score from baseline (cm)
AEs (AEs/ women)
Diagnostic surgery
77.4%
ND
ND
77.4%
+0.3
0/31
Lesion excision
11.8% (3.6–22.2%)
25.0% (4.4–41.7%)
15.8% (0.0–42.0%)
22.6 (5.8–56.9%)
–3.6
124/1527
Lesion ablation
11.4%
ND
ND
ND
–2.4
0/79
Endometrioma drainage only
ND
ND
54.8 (52.9–75.0%)
51.5% (22.9–80.0%)
ND
0/32
Pelvic denervation
6.7% (5.8–15.0%)
34.3% (8.6–48.1%)
28.7% (10.0–36.0%)
12.5%
–2.2
27/182
Hysterectomy with ovarian preservation
ND
ND
ND
19.1%
ND
ND
Hysterectomy without ovarian preservation
ND
ND
ND
8.0%
ND
ND
DIE
0.0% (0.0–4.4%)
2.3% (2.2–4.4%)
7.0%
4.1% (1.3–27.6%)
–6.2
63/779
Singh S et al., submitted
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PRECONGRESS COURSE 03 I VIENNA, AUSTRIA – 23 JUNE 2019 165