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Healthy patients with antiphospholipid antibodies
• No evidence-base
• Offer regular review
• Maximise lifestyle choices and reduce obesity
• Thromboprophylaxis at time of haemostatic stress
• Contraception - POP, Depo-Provera, Mirena coil
• HRT- transdermal HRT, clonidine
• ALIPAS – ARC study – open comparison of low dose warfarin v aspirin closed due to poor recruitment
• PLEASE DON’T GIVE ASPIRIN!
Aspirin and All-Cause Mortality in 14 Primary Prevention Trials.
PM Ridker. N Engl J Med 2018;379:1572-1574.
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