Page 24 - ESHRE2019

Chromosomal disorders: embryo
100
90
80
70
60
50
40
30
20
10
0
Embryonic karyotype
2 3 4 5 6 >7
n=1309 women,
2‐20 miscarriages in the 1. trimester
Ogasawara M, et al (2000): Fertil Steril 73: 300-4
Medizinische Universität Innsbruck
number of miscarriages
normal pathological
Chromosomal disorders: embryo
• PGS (Preimplantation Genetic Screening) • PGD (Preimplantation Genetic Diagnosis)
ESHRE PGD Consortium
Medizinische Universität Innsbruck
6000 5000 4000 3000
PGS
social sexing
sexing for X-linked disorders
2000 chromosomal abnormalities monogenic disease
1000 0
22
19
percentage [%]
I (1997-1999)
II (2000)
III (2000-2001)
IV (2001)
V (2002)
VI (2003)
VII (2004)
VIII (2005)
IX (2006)
X (2007)
XI (2008)