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Implantation process Influence of age on oocyte quality 6Mitochondria viability per age group 4x x 2 x 0 <35 years ≥35 years 108 P<0.001 108 108 Mitochondrial function impaired (less energy) Granulosa cell apoptosis increased (quality) Oxidative stress increased (quality) Ben-Meir et al. Aging Cell 2015 Weall et al. Reproduction 28015 48 45 Mean fluorescent intensity (pixels x 103/μm2)
