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 The embryo is chromosomally mosaic
   Vanneste et al., Nature Medicine, 2009
  Analysis of genome of all blastomeres at different stages of development
       Day 0 Day 1 Embryonic stage zygot
e
Day 2
Day 3
Day 4 Day 5 Day 6 Day 7 morula blastocyst
Days after fertilization
2‐cell
4‐cell
8‐cell
                                                                                                Euploid cell
Cell with acquired monosomy
Cell with acquired trisomy
Euploid cell in inner cell mass (ICM) Euploid cell in trophectoderm (TE) Missegregation error
                        Fernandez et al., unpublished
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