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Mosaicism Reporting
88% of clinics opt out of reporting mosaicism 74% of clinics do not use mosaicism testing
Key Points
• Mosaicism exists, but is rare
• Overestimation to argue PGT‐A can’t work and to gain commercial
advantage
• General lack of acknowledgement of technical limitations and artifacts
• Clinical diagnosis from a single biopsy provides poor predictive value
• Validation is extremely limited
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