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Progesterone Receptor (PgR)
• Reliable predictive factor for disease response
• Routine check is not recommended
• > 50% of PgR negative patients will respond to treatment
Yamazawa K, et al, Hum Reprod 2007; 22: 1953–1958
Reproductive Outcomes
1. Not all women with EC will achieve CR with progestins
2. Among those who will achieve CRnot all will attempt pregnancy
3. Pregnancy rates vary, as the meaning of a successful outcome
Consider IVF referral
• Pregnancy is associated with reduced risk of EC recurrence
• Pooled live birth rate was 28%with IVF 39%
Park JY, et al, Eur J Cancer 2013; 49:868
Koskas M, et al, Fertil Steril 2014; 101:785
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