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 Clear‐cell Ca ‐ stage I
Recurrence
• is extra‐ovarian and lethal
• very early within the first 2 years after surgery
• 17%
• Disease Free Survival and Overall Survival did not demonstrate any significant difference after FSS
Park JY. Int J Gynaecol Obstet 2016
 OCCC and FSS
• National Cancer Institute's Surveillance, Epidemiology, and End Results (SEER) data
• stages IA ‐ IC (Nasioudis et al. J Gynecol Oncol 2017)
• preservation of uterus and ovary did not affect the survival outcomes
• main reason for not recommending FSS in OCCC was the concern about poor survival outcomes
• Recent studies suggested that the survival outcomes of early stage OCCC are similar with other histologic types (Okamoto M, et al. 2013 J Gynecol Oncol)
(Miyamoto A et al. Int J Gynecol Cancer 2014)
• Further studies are needed to confirm the safety of fertility‐sparing surgery in OCCC
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