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GRADE
• Qualityofevidenceperoutcome(notperstudy)
• Focussonappropriateevidenceratherthanonlyon whether a SR or RCT
Beyond the evidence
Recommendations for clinical practice
‐ Evidence
‐ Benefits versus harms
‐ Values (patients)
‐ Resource use
‐ Health system perspective ‐ Acceptability
‐ Feasibility
Best evidence
Clinical expertise
Patient preferences
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