Page 144 - ESHRE2019
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Non-alcoholic fatty liver disease presents major clinical challenges
Healthy Liver Fatty Liver Fatty Liver + Cirrhosis Inflammation
No mechanisms to stratify the disease or to predict outcome
New drugs can not be used in a targeted manner
Cell clumps
CDM + Activin + FGF2 (No feeders / No serum)
hESCs / hIPSCS and organoid
Oct-4 / Sox2 / Klf4 / C-Myc?
Somatic cells. (Skin Cells)
CDM + Activin + FGF2 (No feeders / No serum)
iPSCS
hESCs
Organoid
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