Page 62 - ESHRE2019
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Learning Objectives
Chromosomal instability in human pluripotent stem cells:
• Type and frequency of chromosomal abnormalities in hiPSCs and hESCs • Mechanisms leading to chromosomal instability hPSCs
• Culture heterogeneity
• Exogenous effects on chromosomal stability
• Implications for clinical applications
The promise and challenge of hPSCs
hPSCs are known to acquire chromosomal abnormalities as they proliferate and differentiation
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