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The potential of hPSC
• By definition, a pluripotent stem cell can differentiate into cells of all three germ layers (endo-, meso-, ectoderm) = any cell type of the adult human body
• Differentiation towards a specific cell type is a step-wise mechanism
D’Amour et al., 2016
Differentiation potential of hPSC
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The potential of hPSC
• In-vitro model for development and disease
• Drug discovery and testing
• Cell source for regenerative
medicine
• Gene therapy
Differentiation potential of hPSC
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