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Insulin Sensitizers- Targets & Effects
SLIDE 6
Insulin Sensitizers- Mode/s of Action
• Metabolic -Lipid synthesis
-Gluconeogenesis -Glucose
- SHBG/HDL
• Endocrine - Insulin
- IGF-1
- Androgens
• Anti-inflammatory - TNFa
- CRP
• Anti-angiogenic -VEGF
• Anti-carcinogenic - Insulin
- IGF-1
Lauretta R, et al. Insulin-Sensitizers, Polycystic Ovary Syndrome and Gynaecological Cancer Risk. Int J Endocrinol. 2016:8671762.
SLIDE 7
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