Page 56 - ESHRE2019

3. Blinding: Participants and personnel
Outcome: Clinical pregnancy +
On the day of oocyte retrieval participants were randomly
allocated to either IM progesterone (50mg/daily) or a vaginal
1 ring (1g of progesterone). HCG was measured 12 days after +
embryo transfer.
Patients were randomised for IUI in a natural cycle or for IUI - in a cycle with ovarian stimulation [challenge!]
Participants were randomised to either IUI or no treatment for three consecutive cycles.
All participants and trial personnel were masked to treatment + assignment for the duration of the trial. Placebo capsules
were identical in taste and appearance to the Vitamin A
capsules
Patients were randomised to either endometrial scratching ?
during days 1-12 of their menstrual cycle, or a placebo
5 procedure which involved placing the pipelle in the external
os only. Participants then tried to conceive for the three following cycles
2
3
4
Sources of bias
Selection Performance Detection Attrition Reporting
Target population Allocation
Intervention group
Outcome assessment
Control group
Outcome assessment
Blinding of outcome assessors
Publication of study outcomes
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