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Which trials focused on inherited thrombophilia?
• Single pregnancy loss > 10 weeks (Gris, 2004, in meta‐ analysis)
• FRUIT (de Vries, 2012, in meta‐analysis)
• TIPPS (Rodger, 2014, in meta‐analysis)
Skeith, Blood 2016; Rodger, Lancet 2016
LMWH for late pregnancy complications
No reduction in recurrent complications (n=963) 14% versus 22%
RR 0∙64, 0.36 ‐ 1.11
In multi‐center trials: 18% versus 18%
Rodger, Lancet 2016; EPPI trial Groom Am J Obstet Gynecol 2017
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