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Polycystic ovary syndrome
• Characterised by anovulation with clinical (hirsutism/acne) and/or biochemical evidence of androgen excess
• Clinical, endocrine and metabolic phenotype is heterogeneous and is affected by ethnicity and environment
• Typically presents during adolescence
• Affects >5% women of reproductive age
• Commonest cause of menstrual dysfunction (>80% cases of anovulatory infertility) and hirsutism
• Typical endocrine features are raised testosterone and LH
• Also associated with metabolic abnormalities and increased risk of type 2 diabetes
Pathophysiology of polycystic ovary syndrome
• Presentation and prevalence
• Endocrine and metabolic features
• Impact on reproduction and long term health • What do we know about causes of PCOS?
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PRECONGRESS COURSE 07 I BARCELONA, SPAIN – 1 JULY 2018 13