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Diagnostic criteria for PCOS
NIH 1990
• Chronic anovulation
• Clinical and/or
biochemical signs of
hyperandrogenism
(with exclusion of other aetiologies, eg CAH)
(both criteria needed)
Rotterdam 2003
• Oligo- and/or anovulation
• Clinical and/or biochemical signs of hyperandrogenism
• Polycystic ovaries
(2 of 3 criteria needed)
Zawadzki & Dunaif 1992, in Polycystic Ovary Syndrome, Dunaif et al (eds), Boston: Blackwell Scientific pp 377-84 Rotterdam ESHRE/ASRM sponsored PCOS Consensus Workshop Group (Hum Reprod 2004 19 41-7)
Pathophysiology of polycystic ovary syndrome
• Presentation and prevalence
• Endocrine and metabolic features
• Impact on reproduction and long term health • What do we know about causes of PCOS?
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