Page 68 - PCC07
P. 68

                  i
e
in
h
hi
nP
is
s
w
Po
ol
l
y
‐ ‐ ‐
PCOM on ultrasound
Non specific for PCOS
Variable across life stages Technical and other challenges
Changes:
‐ ‐
Not recommended adolescents <8 years post menarche
Not needed in adults if HA + irregular cycles
  T
T
wo
or
yc
c
rk
ki
y
ys
st
i
s
t
s
s
i
i
c
c
O
su
up
Ov
p
v
a
p
p
a
r
o
or
ry
rt
yS
t
e
e
d
Sy
y
db
n
n
d
b
dr
y
y
t
ro
o
m
th
he
m
e
eN
e(
NH
(p
HM
pr
M
ro
o
j
R
RC
je
e
c
C
f
c
t
tn
fu
un
nu
u
m
nd
de
mb
ed
b
e
dC
er
Ce
rA
A
en
P
P
nt
P
P
t
r
re
1
1
e
f
0
0
fo
o
r
7
78
r
R
84
Re
4
es
4
4
se
4
ea
4)
)
a
r
.
.
r
c
ch
hE
E
x
x
c
ce
e
l
l
l
le
en
n
c
ce
   i
e
in
n
P
P
o
o
l
ly
yc
cy
Anti‐Müllerian Hormone (AMH)
                              ys
st
t
i
ic
cO
O
v
va
Clinical Questions
• •
Is AMH effective for diagnosis of PCOS? Is AMH effective to diagnosis of PCOM?
 EBR
Serum AMH levels should not yet be used as an alternative for the detection of PCOM or as a single test for the diagnosis of PCOS
***
ÅÅoo
CPP
 There is emerging evidence that with improved standardisation of assays and established cut off levels or thresholds, based on large scale validation in populations of different ages and ethnicities, AMH assays are becoming more accurate in the detection of PCOM.
_
_
          a
r
ry
y
S
S
y
y
n
nd
d
r
r
o
o
m
me
e(
(
p
pr
r
o
oj
j
e
ec
c
t
t
n
n
u
u
m
mb
b
e
d
C
e
r
r
A
C
e
e
A
P
n
nt
P
P
tr
re
P1
ef
10
fo
or
07
r
R
78
Re
84
es
44
s
e
44
e
4
)
a
ar
).
.
rc
ch
hE
Ex
xc
c
e
e
l
l
l
le
en
n
c
ce
Teede et al Human Reproduction 2018
 T
Th
h
i
i
s
s
w
w
o
o
r
r
k
k
i
i
s
ss
s
u
u
p
p
p
p
o
o
r
rt
t
e
e
d
d
b
b
y
yt
th
he
e
N
N
H
HM
MR
R
C
Cf
fu
un
n
d
de
e
d
 Page 61 of 196
 68
   66   67   68   69   70