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Non‐invasive calcium measurement
Particle Image Velocimetry (PIV)
Adjuk et al., Nat Commun 2011; Swann et al., Fertil Steril 2012
Future perspectives
• Set strict inclusion criteria
• Develop “the most efficient/safest” AOA protocol • Recombinant PLC RNA/protein?
• Register long‐term developmental outcomes following ICSI‐AOA
• Future trials will be limited by the relative infrequency of failed
fertilization following ICSI
• Should we rescue defective gametes? Or rather focus on ways of improving gametogenesis?
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