Page 138 - ESHRE2019
P. 138

 Human urine proteome: more than 6000 proteins
6085 proteins were identified in urine from 24 healthy individuals (12 females, 12 males), concentrations were determined for 2571 proteins (range 106).
Zhao M. et al. 2017
Urine includes a large number of proteins originating from the reproductive tract.
  Human urine proteome database:
http://www.urimarker.com/urine
endometrium 1165 proteins
uterine cervix 870 proteins
fallopian tube 1144 proteins
ovary 469 proteins
vagina 533 proteins
11
  Human metabolome represents the closest link to the phenotype
„The human metabolome represents the complete collection of small molecules found in the human body including peptides, lipids, amino acids, nucleic acids, carbohydrates, organic acids, biogenic amines, vitamins, minerals, food aditives, drugs, cosmetics, contaminants, pollutants, and just about any other chemical that humans ingest, metabolize, catabolyze or come into contact with.“
 Metabolites
Number
Total
114 100
Detected & quantified
18 557
Detected not quantified
3 271
Expected
82 274
Predicted
9548
 www.hmdb.ca
HMDB 4.0 for 2018
Wishart et al. 2018
 12
 136
133
 


































































   136   137   138   139   140