Page 166 - ESHRE2019

Introduction: Organ transplantation
• Absolute uterine factor infertility (AUFI) • Affects 1/500 women of fertile age.
• Acquired & Congenital AUFI.
• Options:
• Gestational surrogacy.
• Uterine transplantation. (Brännström et al., 2015)
2015‐2016 Live donor
Deceased donor
Dec. 2018
Innovation
Foundation
Introduction: Organ transplantation
 Shortage of organs.
 Logistics, ethical concerns.
 Organ preservation.
 Best case scenario Brazil: 3500 donors annually.
 Transplantation after circulatory death (DCD).
 Life-long immunosuppression side effects.
 F.e. morbidity, kidney disease, susceptible to infections, cardiovascular risks,...
“But because of the surgery and the immunosuppression (anti-rejection drugs), it produced an infection, and that infection invaded the (blood) vessels of the uterus, and it caused a failure.”
Possible solution to be found in Regenerative medicine
Innovation
Foundation
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