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Medical treatment
Imaoka,I., Ascher,S.M., Sugimura,K. et al (2002) MR imaging of diffuse adenomyosis changes after GnRH analog therapy. J.Magn Reson.Imaging, 15, 285-290.
LH-RH agonist therapy in 30 women with diffuse adenomyosis
– 12symmetric
– 18 asymmetric with focal high IS(intensity signal) foci
– Decrease in JZ thickness P<0.0001
– Disappearance of high ISfoci
– Asymmetric adenomyosis with high SI foci appears to be the most sensitive to hormonal therapy
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onclusion: This study demonstrates that adenomyosis, taken from
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Medical treatment
patients treated with dienogest, shows remarkable histological features, such as reductions in proliferation, NGF expression and nerve fiber density. These findings indicate the impact of dienogest on local
Conclusion:
This study demonstrhiasttoelogsicatlhevaenttsa, adndeenxpolamins yitsothseirsap,etutaickeeffenct ofnroadmenompyaostisi.ents treated with dienogest, shows remarkable histological features, such as reductions in proliferation, NGF expression and nerve fiber density. These findings indicate the impact of dienogest on local histological
events, and explains its therapeutic effect on adenomyosis.
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