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The case for Hepatitis E
Hepatitis E virus is a water‐borne pathogen that has fecal‐oral transmission, mostly due to contaminated water. Person‐to‐person transmission is uncommon. The incubation period has a mean of 6 weeks. The rate of vertical transmission is 50%.
Each year about 20 million cases of HEV infection occur globally, with 70 000 deaths. Hepatitis E virus was first recognized in 1978 during an epidemic in Kashmir Valley in northern India, with 52 000 cases of hepatitis resulting in 17 000 deaths.
Hepatitis E is a single‐stranded RNA virus with 4 genotypes, of which genotypes 1 and 2 exclusively infect humans and can lead to endemic HEV or outbreaks in countries with poor sanitation systems.
HEV is an important contributor to maternal morbidity and mortality (15 to 25%) especially if infection occurs in the third trimester with genotype l.
Antigenic challenge in sexual
reproduction
• Semen, which does not travel alone. Seminal plasma and male genital microbiota must be taken into account
• Placenta. Which can be intact, can rupture during pregancy, must separate itself from the uterine wall after delivery
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