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Vaccination during pregnancy
• Livevaccinesarecontraindicatedduringpregnancy and during the 4 weeks preceding the pregnancy
• Contraindicationsarebasedontheoreticalrather than documented risks
• MMRnotlinkedtofetalinfection,congenital anomalies or other severe outcomes
• Inadvertent administration of any of LV is not considered an indication for termination of the pregnancy
• A true contraindication is hypersensitivity to any vaccine components.
Vaccine Formulation
• Vaccines contain besides the antigen(s) many types of additives, excipients, preservatives, stabilizers, antibiotics, and adjuvants
• Liquid or lyophilized
Antigen
Preservatives
Antibiotics
(gelatin, albumin)
Suspension liquid
Adjuvants
Stabilizers
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